Davis v. Takeda Pharmaceuticals USA Incorporated et al

Filing 11

TRANSFER ORDER re: pldg. ( 1 in MDL No. 2789) Transferring 100 action(s) to Judge Claire Cecchi in the D. New Jersey.Signed by Judge Sarah S. Vance, Chair, PANEL ON MULTIDISTRICT LITIGATION, on 8/2/2017. Associated Cases: MDL No. 2789 et al. (LAH)

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UNITED STATES JUDICIAL PANEL on MULTIDISTRICT LITIGATION IN RE: PROTON-PUMP INHIBITOR PRODUCTS LIABILITY LITIGATION (NO. II) MDL No. 2789 TRANSFER ORDER Before the Panel:* Plaintiffs in 24 actions pending in the District of New Jersey move to centralize this litigation in that district, or, in the alternative, the Southern District of Illinois. The litigation consists of the 161 actions listed on the attached Schedule A. The Panel has been informed of 34 additional federal actions involving related issues.1 All responding plaintiffs support centralization, but certain plaintiffs argue, in the first instance, for the Southern District of Illinois. Defendants’ positions on centralization vary. Defendants AstraZeneca Pharmaceuticals LP and AstraZeneca LP (AstraZeneca) support centralization in the District of New Jersey or the Central District of California. Defendants Pfizer Inc., Wyeth Pharmaceuticals, Inc., Wyeth, LLC, and Wyeth-Ayerst Laboratories (collectively Pfizer) support centralization in the District of New Jersey (or, in the alternative, the Eastern District of Pennsylvania). Defendants Procter & Gamble Company and The Procter & Gamble Manufacturing Company (P&G) do not oppose centralization in the District of New Jersey. Various Takeda defendants (Takeda)2 oppose centralization, and do not suggest any transferee district, if centralization is ordered over their objections. Novartis Consumer Health, Inc. (NCH), which is sued only in a potential tag-along action (in which Takeda also is a defendant), also opposes centralization, and, if centralization is ordered over its objections, advocates the District of New Jersey or the Eastern District of Pennsylvania. Both Takeda and NCH further argue that if an MDL is created, any cases or claims against them should be excluded. Finally, three other Novartis entities – Novartis Pharmaceuticals Corporation, Novartis Vaccines and Diagnostics, Inc. and Novartis Institute for Biomedical Research, Inc. – oppose centralization on the grounds that they are not * Judge Marjorie O. Rendell took no part in the decision of this matter. 1 These and any other related actions are potential tag-along actions. See Panel Rules 1.1(h), 7.1, and 7.2. 2 Takeda Pharmaceutical Company Limited, Takeda Pharmaceuticals U.S.A., Inc., Takeda Pharmaceuticals International, Inc., Takeda Development Center Americas, Inc., Takeda California, Inc., Takeda Pharmaceuticals America, Inc., Takeda GmbH, Takeda Pharmaceuticals LLC, and TAP Pharmaceutical Products, Inc. -2current or former manufacturers or developers of any of the pharmaceuticals at issue, and thus are not proper parties. I. In the complaints in these 161 personal injury and wrongful death actions, plaintiffs allege that as a result of taking one or more proton-pump inhibitors (PPIs), they or their decedents suffered kidney injury (e.g., chronic kidney disease (CKD),3 acute interstitial nephritis, end stage renal disease, or kidney failure). Plaintiffs allege that defendants failed to adequately warn of the negative effects and risks associated with PPIs. This litigation is before us for the second time this year. At our January hearing session, we denied a motion for centralization brought by plaintiffs in six PPI actions. In re: Proton-Pump Inhibitor Prods. Liab. Litig. (Proton-Pump I), — F. Supp. 3d —, 2017 WL 475581 (J.P.M.L. Feb. 2, 2017). The motion encompassed fifteen constituent actions and 24 potential tag-along actions pending in a total of seventeen districts. Id. at *1. All defendants opposed centralization. Id. In Proton-Pump I, we recognized that the actions shared certain factual issues “arising from plaintiffs’ allegations that taking [PPIs] may result in various types of kidney injury,” including the conditions listed above. Id. But we concluded that centralization was not warranted for a number of reasons. First, the named defendants varied from action to action: AstraZeneca was sued in most of the actions (14 constituent actions and 23 tag-alongs), but P&G was sued in only eight, Takeda in four, and Pfizer in two. We thus reasoned that centralization “appear[ed] unlikely to serve the convenience of most, if not all, defendants and their witnesses.” Id. Second, defendants were (and still are) competitors, and centralizing them in a single MDL “likely would complicate case management due to the need to protect trade secret and confidential information,” and might prolong pretrial proceedings, because of, inter alia, the possible need for separate discovery and motion tracks, as well as additional bellwether trials. Id. at *2. Third, we found that a significant amount of discovery was “almost certain to be defendant-specific,” given that the drugs at issue were “not identical,” with each having “a unique development, testing, and marketing history, and each [having been] approved by the FDA at different times.” Id. We stated that the differences among the drugs, as well as the variety of injuries alleged, “significantly undermine[d] any efficiency gains to be achieved from centralization.” Id. Finally, we noted that although moving plaintiffs had “almost guarantee[d]” that the number of actions would increase “by the hundreds if not thousands,” the Section 1407 motion encompassed only 39 cases, including tag-alongs. Id. 3 Plaintiffs in more than 120 of the constituent actions allege that they suffered CKD. -3II. In support of this new motion,4 plaintiffs, AstraZeneca, and Pfizer argue that the number of involved actions, districts, and plaintiffs’ counsel has increased significantly since Proton-Pump I, that many more cases likely will be filed, that there now are a significant number of related state court actions,5 and that informal coordination and cooperation are not practicable to manage litigation of this scope. After careful review of the record, we agree with this assessment. As stated above, these actions share factual issues arising from allegations that taking one or more PPIs can result in kidney injury, and that defendants failed to adequately warn of the negative effects and risks of PPI use. Although several of the grounds on which we denied centralization in Proton-Pump I remain largely valid,6 we find that the significantly larger number of involved actions, districts, and counsel, the concomitant increase in burden on party and judicial resources, and the opportunity for federal-state coordination, coupled with most defendants’ change in position to now support centralization, tip the balance in favor of creating an MDL.7 Centralization will facilitate a uniform and efficient pretrial approach to this litigation, eliminate duplicative discovery, prevent inconsistent rulings on Daubert and other pretrial issues, and conserve the resources of the parties, their counsel, and the judiciary. While we do not discount the case management-related difficulties that a multi-product and multi-defendant MDL such as this may entail, the unusual circumstances presented convince us that at this juncture, formal centralization under Section 1407 is the best course. As we repeatedly have stated, a transferee judge can employ any number of techniques, such as establishing separate discovery and motion tracks, to manage pretrial proceedings efficiently. See, e.g., In re: AndroGel Prods. Liab. Litig., 24 F. Supp. 3d 1378, 4 We note that our denial of centralization in Proton-Pump I did not foreclose the filing of this second motion for centralization. That earlier denial also does not preclude us from reaching a different result here. We will do so only rarely, however, where a significant change in circumstances has occurred. See In re: Plavix Mktg., Sales Practices & Prods. Liab. Litig. (No. II), 923 F. Supp. 2d 1376, 1378 (J.P.M.L 2013). 5 AstraZeneca represents that it has been sued in 87 state court PPI actions – 85 in Delaware, one in Missouri, and one in Ohio. 6 The variety of alleged kidney injuries arguably has diminished, as most plaintiffs allege that they suffer from CKD. In addition, the status of defendants as competitors (and defendants’ concerns regarding trade secrets, etc.) may be less of an issue in this litigation, given that most (and possibly all) of these medications no longer have patent protection. 7 See In re: Lipitor (Atorvastatin Calcium) Mktg., Sales Practices & Prods. Liab. Litig. (No. II), 997 F. Supp. 2d 1354, 1356 (J.P.M.L. 2014) (granting follow-up motion for centralization, where number of related actions had grown from 29 in thirteen districts to over 225 in more than 40 districts; the number of involved plaintiffs’ firms had grown as well; and the Panel had been informed of related cases pending in at least three state courts). -41379-80 (J.P.M.L. 2014).8 As with any MDL, the transferee judge has substantial discretion to refine the litigation’s parameters. Id. at 1380 (“[T]he transferee judge retains wide discretion as to how the MDL should be defined . . . .”). If, after close examination, she determines that Section 1407 remand of any claims or actions involving a particular defendant or PPI is appropriate, procedures are available to accomplish this with minimal delay. Id. (citing Panel Rule 10.1). In opposing centralization and arguing that if centralized, any cases and claims against it should be excluded from the MDL, Takeda relies heavily on our decision in Proton-Pump I, and further argues that it is sued in only a minority of the 161 actions. For the reasons stated above, we conclude that Proton-Pump I does not control the outcome here. And, although it is true that AstraZeneca is sued in far more actions than Takeda, a significant number of actions are “mixed use” cases in which the plaintiffs allege use of more than one PPI, and sue Takeda and one or more other PPI manufacturers, including AstraZeneca.9 The prospect of additional cases against Takeda does not seem far-fetched.10 Given these circumstances, including the seemingly indivisible nature of plaintiffs’ alleged injuries in the “mixed use” cases, we decline to carve out from the MDL cases or claims against Takeda.11 8 In Androgel, we ordered industry-wide centralization of all cases alleging injuries arising from the use of testosterone replacement therapies on the grounds that a number of plaintiffs had “used more than one testosterone replacement therapy,” and that “[t]he other approaches proposed by the parties—centralizing only [cases involving AbbVie’s Androgel product] (and perhaps transferring ‘combination cases’), separating and remanding claims against certain manufacturers, or transferring only claims relating to testosterone replacement gels—could prove too procedurally complicated, might result in a de facto industry-wide centralization as cases involving multiple drugs become part of the MDL, or may require successive motions for centralization.” In re: Androgel Prods. Liab. Litig., 24 F. Supp. 3d at 1379. These same circumstances are present in the PPI cases now before us. 9 For example, the Middle District of Florida Lear plaintiff alleges use, at various times, of AstraZeneca’s Nexium and Prilosec PPIs, Takeda’s Prevacid PPI, and Pfizer’s Protonix PPI; the District of Idaho Buzbee plaintiff alleges use of Nexium and Prevacid; the Western District of Louisiana Crandell plaintiff alleges use of Nexium, Prevacid, and Prilosec; the District of New Jersey Luzzo plaintiff alleges use of Nexium and Prevacid; and the Eastern District of Pennsylvania Miller plaintiff alleges use of Nexium and Prevacid. 10 Sales of Prevacid, which came to market in 1995, reportedly exceeded $3 billion annually at one time. 11 Whether claims against NCH, which markets Prevacid 24HR, should be included in the MDL is best addressed through our conditional transfer order process, as NCH is sued only in an Eastern District of Tennessee tag-along action. Similarly, whether future claims against the three other Novartis entities – Novartis Pharmaceuticals Corporation, Novartis Vaccines and Diagnostics, (continued...) -5We select the District of New Jersey as transferee district for this litigation. More than 60 of the 161 constituent actions already are pending in D. New Jersey (more than in any other district). The district is a relatively convenient venue, and enjoys the support of most plaintiffs, as well as the AstraZeneca, Pfizer, and P&G defendants. Further, centralization in the District of New Jersey enables us to assign the litigation to Judge Claire C. Cecchi, an experienced transferee judge who already is actively managing the PPI cases filed in that district. We are confident that the judge will steer this litigation on a prudent course. IT IS THEREFORE ORDERED that the actions listed on Schedule A and pending outside the District of New Jersey are transferred to the District of New Jersey, and, with the consent of that court, assigned to the Honorable Claire C. Cecchi for coordinated or consolidated pretrial proceedings. PANEL ON MULTIDISTRICT LITIGATION Sarah S. Vance Chair Charles R. Breyer Ellen Segal Huvelle Catherine D. Perry 11 Lewis A. Kaplan R. David Proctor (...continued) Inc. and Novartis Institute for Biomedical Research, Inc. – should be transferred to the MDL is not properly before us, as those entities currently are not sued in any of the constituent or tag-along cases (having been voluntarily dismissed from the one action in which they previously were named). IN RE: PROTON-PUMP INHIBITOR PRODUCTS LIABILITY LITIGATION (NO. II) MDL No. 2789 SCHEDULE A District of Arizona DAVIS v. TAKEDA PHARMACEUTICALS USA INCORPORATED, ET AL., C.A. No. 2:16-04485 Eastern District of California THOMAS v. TAKEDA PHARMACEUTICALS USA, INC., ET AL., C.A. No. 1:16-01566 COSTAMAGNA, ET AL. v. THE PROCTER & GAMBLE COMPANY, ET AL., C.A. No. 2:17-00409 Middle District of Florida LEAR v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 3:17-00240 District of Idaho BUZBEE v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 3:17-00174 Central District of Illinois MULLEN v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 1:17-01220 Northern District of Illinois WEITER v. TAKEDA PHARMACEUTICALS USA, INC., ET AL., C.A. No. 1:16-11199 PARKER v. TAKEDA PHARMACEUTICAL COMPANY LIMITED, ET AL., C.A. No. 1:17-03764 Southern District of Illinois COLEMAN, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 3:17-00130 ROSENSTEEL, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 3:17-00131 DRAVLAND, JR. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 3:17-00133 - A2 MDL No. 2789 Schedule A (Continued) RICHARDSON v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 3:17-00406 MCGILL, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 3:17-00461 WINTERS, SR. v. ASTRAZENECA PHARMACEUTICALS, LP, ET AL., C.A. No. 3:17-00535 District of Kansas KOON v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:16-02605 DONECKER v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 6:17-01082 Eastern District of Kentucky CARPENTER v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 0:16-00159 ROBERTS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 5:17-00117 LOCKARD, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 6:17-00125 THACKER, ET AL. v. THE PROCTER & GAMBLE COMPANY, ET AL., C.A. No. 7:17-00078 Western District of Kentucky LOWE v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 5:17-00078 Eastern District of Louisiana LABICHE, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:16-15893 JOHNSON, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:16-16424 TILLMAN v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:16-17742 BALES v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:16-17744 SELF v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:16-17746 LEBLANC v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:16-17748 EDWARDS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:16-17750 DONALD v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:16-17753 MCCOY v. ASTRAZENECA PHARMACEUTICALS, LP, ET AL., C.A. No. 2:16-17903 - A3 MDL No. 2789 Schedule A (Continued) ELLIS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:16-17904 ROGERS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:16-17906 HARTS, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-02298 WILLIAMS v. PROCTOR & GAMBLE COMPANY, ET AL., C.A. No. 2:17-03972 MORRIS v. ASTRAZENECA LP, ET AL., C.A. No. 2:17-04804 BRUNET v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-05114 Middle District of Louisiana DAVIS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 3:16-00686 SMITH v. ASTRAZENECA PHARMACEUTICALS, LP, ET AL., C.A. No. 3:16-00696 Western District of Louisiana CAESAR v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00198 MODICUE v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 6:16-01444 MILLER v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 6:16-01455 CRANDELL v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 6:16-01460 BUSH v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 6:17-00669 District of Maine MCGARR v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 1:17-00183 District of Maryland BURCH v. WYETH PHARMACEUTICALS, INC., ET AL., C.A. No. 8:17-00970 Eastern District of Missouri MILLIGAN v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 4:17-01546 Western District of Missouri GREGG v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 6:17-03101 - A4 MDL No. 2789 Schedule A (Continued) District of New Jersey GOODSTEIN v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:16-05143 SPRATT v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:16-05523 BOYD v. ASTRAZENECA LP, ET AL., C.A. No. 2:16-08121 HUNTER v. ASTRAZENECA LP, ET AL., C.A. No. 2:16-08895 ADKINS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00194 SAVAGE v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00196 PIERRE v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00198 AUBREY v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00201 GILYARD v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00202 TONEY v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00203 WATKINS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00204 STEWART v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00206 GRAVES v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00207 SCOTT v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00208 CARRUTHERS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00211 LEE v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00212 WILBURN v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00213 WILKERSON v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00215 LAYTON v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00216 GUTIERREZ v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00217 HAWKINS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00218 HUDSON v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00219 LLOYD v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00500 MASSENGILL v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00761 GARRISON v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-01207 ELLIOTT v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-01413 JAY, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-01606 MUSE v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-01870 JONES v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-02098 DEVITO v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-02465 FOSTER v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-02475 LUZZO v. ASTRAZENECA LP, ET AL., C.A. No. 2:17-02567 - A5 MDL No. 2789 Schedule A (Continued) STARKS v. ASTRAZENECA PHARMACEUTICALS, LP, ET AL., C.A. No. 2:17-02597 PETTIES v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-02700 ROBERTSON v. ASTRAZENECA LP, ET AL., C.A. No. 2:17-02744 PETERSON v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-02999 HENDERSON v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03056 BOOTHE v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03191 HOLLOWAY v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03192 VALENTINE v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03193 ALLEN v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03197 MORRIS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03200 KELLEY v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03204 HOUZER v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03207 BOULER v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03209 CARROLL v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03210 HUNTER-MALONE v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03211 KILIAN v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03265 LANE v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03302 BOWENS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03316 STUKES v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03343 LAURENT v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03346 ZELLARS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03364 BREWINGTON v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03365 CHISLEY v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03366 BERNARD v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03461 MITCHELL v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03467 LYTTLE, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03562 TACNEAU v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03591 HOWARD v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03594 JONES, JR. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-03606 Eastern District of New York GAGLIO v. ASTRAZENECA PHARMACEUTICAL LP, ET AL., C.A. No. 1:17-02383 HOLBECK v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 1:17-03192 - A6 MDL No. 2789 Schedule A (Continued) Northern District of New York HORNFECK v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 5:16-01243 Western District of North Carolina MOORE v. TAKEDA PHARMACEUTICALS USA, INC., ET AL., C.A. No. 1:16-00364 Southern District of Ohio GOMEZ, ET AL. v. PROCTER & GAMBLE MANUFACTURING COMPANY, ET AL., C.A. No. 1:17-00340 BURNETT v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:16-00894 BUTLER v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00183 Northern District of Oklahoma BELLAMY v. TAKEDA PHARMACEUTICAL COMPANY LTD., ET AL., C.A. No. 4:17-00289 Western District of Oklahoma ROUNDTREE v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 5:17-00432 Eastern District of Pennsylvania COOPER v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00050 STOCKTON v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00051 RUSS, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00052 BALL, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00053 GARRITY, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00054 BROOKINS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00055 VERTREES, ET AL. v. TAKEDA PHARMACEUTICAL COMPANY LIMITED, ET AL., C.A. No. 2:17-00079 - A7 MDL No. 2789 Schedule A (Continued) MARTINEZ, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00080 PACK v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00081 MALLARD, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00082 ROBINSON, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00083 DONALD v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00084 WILLINGHAM v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00095 ANSON v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00096 BURNETT, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00097 HALL, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00098 STAFFORD v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00100 HAMILTON, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00101 KENNEDY v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00102 KING, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00103 BARTLETT, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00104 MILLER, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00105 ROMERO, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00107 CLAXTON v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00138 SWIFT v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00139 PERDEW v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00140 SEGURA v. WYETH, LLC, ET AL., C.A. No. 2:17-00141 KETCHUM, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00142 VALENTINE v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00148 JONES v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00149 GRIGGS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00150 MCDANIEL v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00151 - A8 MDL No. 2789 Schedule A (Continued) LAPOLLA, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00152 PARMS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00153 ADAMS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00154 RUNYONS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00155 NEWELL, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00156 RIGGS, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00157 WHITAKER, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-00160 District of South Carolina ALL, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 1:17-00968 HARRIS v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 6:17-01045 District of Utah CLARK v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 1:16-00160 Southern District of West Virginia CHURCH, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 1:16-07910 KREUGER, ET AL. v. ASTRAZENECA PHARMACEUTICALS LP, ET AL., C.A. No. 2:17-02370

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