Amgen Inc. v. F. Hoffmann-LaRoche LTD et al

Filing 49

DECLARATION re #44 MOTION to Dismiss for Lack of Subject Matter Jurisdiction and Failure to State a Claim by F. Hoffmann-LaRoche LTD, Roche Diagnostics GmbH, Hoffmann LaRoche Inc.. (Attachments: #1 Exhibit Exhibit 1, Part 1#2 Exhibit Exhibit 1, Part 2#3 Exhibit Exhibit 1, Part 3#4 Exhibit Exhibit 1, Part 4#5 Exhibit Exhibit 1, Part 5#6 Exhibit 2#7 Exhibit 3#8 Exhibit 4#9 Exhibit 5#10 Exhibit 6#11 Exhibit 7#12 Exhibit 8)(Huston, Julia)

J&J, Amgen Caution on Anemia Drugs

Case 1:05-cv-12237-WGY

Document 49-13

Filed 04/11/2006

Page 1 of 1

Page 1 of 1

EXHIBIT 8

Biotech/Pharmaceuticals

J&J, Amgen Caution on Anemia Drugs
By Althea Chang TheStreet.com Staff Reporter
12 /2/ 20 05 5:46 PM EST

URL: http://www.thestreet.com/stocks/biotech/10255421.html

Updated from Dec. 1 Health-care giant Johnson & Johnson (JNJ:NYSE) and big biotech Amgen (AMGN:Nasdaq) issued warnings on three drugs, saying that, in very rare cases, the treatments could actually worsen the disease they're intended to fight. The warnings posted on the Food and Drug Administration's Web site Thursday apply to Johnson & Johnson's Procrit and Amgen's Epogen and Aranesp, which are all designed to treat anemia, a condition marked by a low count of red blood cells. According to the companies, a handful of patients receiving the drugs experienced severe anemia, with or without other blood disorders called cytopenias, in reaction to the drugs since being launched. Amgen spokeswoman Mary Klem said fewer than half a dozen patients taking Epogen, which has been on the market since 1989, and two patients on Aranesp, available since 2002, have experienced this type of reaction. The companies say the drugs should be permanently discontinued in patients with a condition known as antibody-mediated anemia. However, if the drugs are used "in accordance with the approved prescribing information, the benefit/risk profile" of the three drugs continues to be favorable, the companies said.

http://www.thestreet.com/pf/stocks/biotech/10255421.html

3/7/2006