Amgen Inc. v. F. Hoffmann-LaRoche LTD et al

Filing 312

BRIEF by Amgen Inc. CLAIMS CONSTRUCTION BRIEF. (Attachments: #1 Appendix A#2 Appendix B(part 1 of 4)#3 Appendix B (Part 2 of 4)#4 Appendix B (part 3 of 4)#5 Appendix B (Part 4 of 4)#6 Exhibit 1#7 Exhibit 2#8 Exhibit 3#9 Exhibit 4#10 Exhibit 5#11 Exhibit 6 (Part 1 of 2)#12 Exhibit 6 (Part 2 of 2)#13 Exhibit 7#14 Exhibit 8#15 Exhibit 9 (Part 1 of 2)#16 Exhibit 9 (Part 2 of 2)#17 Exhibit 10#18 Exhibit 11 (Part 1 of 2)#19 Exhibit 11 (Part 2 of 2)#20 Exhibit 12#21 Exhibit 13#22 Exhibit 14 (Part 1 of 2)#23 Exhibit 14 (Part 2 of 2)#24 Exhibit 15#25 Exhibit 16#26 Exhibit 17#27 Exhibit 18#28 Exhibit 19 (Part 1 of 2)#29 Exhibit 19 (Part 2 of 2)#30 Exhibit 20#31 Exhibit 21#32 Exhibit 22#33 Exhibit 23#34 Exhibit 24#35 Exhibit 25#36 Exhibit 26)(Gottfried, Michael)

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Case 1:05-cv-12237-WGY Document 312-15 Filed 03/05/2007 Page 1 of 8 EXHIBIT 8 07499800 CTI-MA 308411076MA 645 32724 -1- A .�-�Dp r�v a swo�s 2 �iF fo noitmne�r �p� a si �GH m�hw ,12 �u� S� m ed� si e�efcRe� � gni�occa fo �cu� fo :� ,12 �u� g�ollof S.GIF ot � si t� e� d� �et f� e�� do e� �l� ��lp ,0�/! fo 5 e� g�o�of eteled ,� �t� � s� �� e�lp ni tresni d.�a ]elpmaxE[ esaelp ,42 enil ,22 egap t�.'t NOITACIFICEPS EHT NI .stnemdnema gniwollof eht retne e�elP :riS 13202 CD ,notff�lsaW stnetaP ruf renoissimmoC tnatsissA r�. � NITEIOPORHTYRE FO NOITCUDORP :roF .D.hP ,llemtraM semaJ :renimaxE 3361 :tinU trA 3991,2 tsuguA :deliF pu�nC 7�1,00I/80 :oN ladeS niL �K-uF :fo noit�ilppA ,p Case 1:05-cv-12237-WGY Document 312-15 Filed 03/05/2007 Page 2 of 8 17499800 CTI-MA 408411076MA 745 42724 A -2- f� ecalp � � d� � elbaT[ eteled ebelp ,92 e�l ,�4 eg� �A � f� �c�lp ni msni dx� ]nireht[ eteled esaelp ,31 enll ,94 eg�"� -.eneg OsIECS eht fo 3 noitces eht swohs 12 .sedi�oelcunosilo 3 noitces OPEC$ eht swohs 02 erugiF .eneg OPECS eht fo 2 noitces swohs 91 erugiF .seditoeleunogilo 2 noitces OPEC$ eht swohs 81 erugiF .ene8 OPECS eht fo noitces swohs 71 erugiF erugiF .seditoelcunogilo noitces OPECS eht swohs 61 .eneg OFEEE eht fo 3 uoit�s swohs 51 erugiF .seditoelcunogJlo 3 noitces O�FCE eh� swohs 41 erugiF .eneg .OP._FCE eht fo 2 no/tces swohs 31 erugiF .�-edito�lcunogilo 2 noit�s O�ICE eht �wohs 21 erugiF .eneg OPECE eht fo noitces swohs 11 erugiF .seditoelcunogilo noitces OPECE eht swohs 01 erugiF .seditpepylop OPE yeknom dna namuh eht fo nosirapmoc a swohs 9 erugiF .eneg ORFCS eht fo ecneu�s eht swohs 8 erugiF .eneg OPECE eht fo ecneuqes eht swohs �" erugiF .OPE dedocne eht dna AND OPE cJmoneg namuh fo ecneuqes eht wohs )6 eeugiF sa ot derrefer ylevitcelloc( E"6 dna D6 ,C6 .B6 ,A6 serugiF .ORF del ,rae eht d�a ANDe OPE yeknom fo ecneuqes eht wohs )5 erugiF sa oI B5 ,A5 exugiF erugiF swohs 4 derrefer ylevitcelloc( C� dna .OPEuI-Ig-LVSDp rot�v .OPEuHsVSp rotcev swohs 3 erugiF Case 1:05-cv-12237-WGY Document 312-15 Filed 03/05/2007 Page 3 of 8 27499800 CTI-MA 508411076MA 845 52724 A -3- .12 hguorht S�IUGH sgniward lamrof desolcne eht dda esaelP SGNIWARD � NI .36 16 smialc lec� e� e� SMIALC �I-IT �I foere� eca|p ni tresni dna ]esnpo�[ eteled esaelp ,4 enil ,09 .-)51 dna 31 SERUGH(--foereht ecalp ni tresni dna ])]]]X dna IX selbaT([ eteled emelp ,12 enil ,37 gniHe� eht �erroc esaelp ,03 enil egap ."tnanibmocer'fo egapJ .-.enarbmem- foereht ecalp ni �e�ri dna ]enarbmem[ eteled esaelp ,02 cnll ,36 ,46 t� cgap/(� Case 1:05-cv-12237-WGY Document 312-15 Filed 03/05/2007 Page 4 of 8 37499800 CTI-MA 608411076MA 945 62724 A -4- ot selpmaxE .stnemgarf esoht fo gnic�,cuqcs dica o�ima eht dna stnemgarf citp� ecudorp )"OP,.F yraahtuC aimena ,,itsalpn htiw detciltfa stneitap fo eniru eht morf deta|osi fo selpmaxe sa nifeiop�htyre na�h fo em eht sesolcsid lareves ni desolcsid si 46 mialC ni deticer elpmaxE .noitacilppa eht niteiopo'�in)re namuH .26 dna 16 smialC elbawolla ylsuoiv:np fo �ttam t'gtjbus eht htiw �cdi�nioc dna nimubla trams namuh htiw dexim aitciopothlyr� gniniatnoc noitaup:�rp laoit�.ccamrahal a m detcerid si 56 mialC ylweN .�mtlt� ni �worg sllec nailammam morf deniatbo si hcihw niteioporh.�� a ot det,eid si 46 mialC dedda ytwcg dedda namah fo noitisopmoc lacitaeca�mahp era .dellecnac ybereh itna noitacilpp� eht ni gnidnep erew 36-16 �a-�lC .3102 ,02 tsuguA si hcihw fo etad noitaripxe tseilrae eht ,892,658,5 dna ;080,126,5 ;339,745,5 .soN tnetaP .S.U rof srenkalcsid tnacilppA ,weivcetni eht ta detafidni sA lanimret htiwereh gnilif si s'notnatS renimaxE .doirep siht tuohguorht seififtqn; sutats suoreman sih ot sesnopser tpmorp detaicerppa tnacilppA .puorg gninimaxE eht ot draoB eht morf dem.uter siht saw noitacilppa eht nehw yltnecer litnu emit taht ecnis dednepsus deniamer � dna ecnercf-mni laitnetop a fo noitaredisnoc rof �991 ,I� hcraM no eciffO eht yb dedn�lSUS saw noitacilppa s� fo noitu�orp taht scton tnacilppA ,drocer cht roF .noitacilppa gninrecnoc ,9991 ,12 lirpA no dleh weivr�a/eht rof notnatS renimaxE yrosivrepuS dna lleninafb renimaxE ot noitai�rppa sih sesserpxe tnacilppA .rettam wen yna ecud>ntni ton od dna 868,1;�,,5 .oN tnetaP .S.U sa deussi hcihw 971,311/70 .oN lai'�S noitacilppa tnetap fo taht htiw enil ni noitacificeps eht fo txet eb lliw �6 dna 45 muhc ,stnemdnema det�uqetovoba eht fo � �OPU Case 1:05-cv-12237-WGY Document 312-15 Filed 03/05/2007 Page 5 of 8 47499800 CTI-MA 708411076MA 055 72724 A -5o� ton woh gninrecnoc dedivorp si noitamrofni on esuaceb gnilb�re.non si dna elbataeper si ,315,773�4 .S.U ,ecn ,crefer momiguS eb� t�t noitisop sih sctar�ti�r tna. cilppA fo a .��ioporhcyr� c�c'.�orp ot tnuoma cvitccffc yllacituepareht a fo noitisopmoc lacituecamrahp �rusol�lc tnit eht s�w noitacilppa tneserp ehT .noitaraperp eht ni nimubla ecruos mures namuh htiw dexim si OPE eht taht yficeps seod tub OPE eht fo eht timil ton seod 56 mialC dedda ylwen ,46 mialC ot tsartnoc nI .o-uiv ni snaem hcihw ,erutluc ni nworg cra �lt ).cte ,SOC ,OHC ,namuh( sllec nallamm�m yb decudorp )KIE yna odulcni ot dednetni si esarhp sihT ".erutluc ni nworg sllec nai�mm morf deifirup" essrhp eniru namuh morf d�alos� si n� OPE sedulcxe ,revewoh ,� mialC .noitcudorp eht yb rof desu llec tsoh eht nopu gnidneped reit/d yam n�eioporhtyve ns�u. hfo noi�alysocy]� e� taht sesolcsid.�ebtruf noitacilppa ehT .sllec nailammam rehto ni ro sllec n�nub ni decudo�l eb yam dna �niru namuh arolf d�alosi � fo dica onima eht g�ivah cddp�lylop ym edulcni ot dootsrednu si nitcioporhtyrc namuh ,suhT .ylevitcepser �coe�qcs sllec OHC dna 1-SOC ni ni�iopoultyre namuh fo noitcudorp eht esolcsid 01 dna 7 Case 1:05-cv-12237-WGY Document 312-15 Filed 03/05/2007 Page 6 of 8 57499800 CTI-MA 808411076MA 155 82724 A -6- 1-09606 LI ,og�cikC 53 xoB .O.P DYOLL & DYOB ,LLEB :ot ecnednopserroc eavuf lla dnes esaelP q �-�-� :ctaD 477�8� )075( enohP 345,33 :.oN noitartsigeR )s(tnacilppA rof yemo�A ,denimbuS ylluftcepseR .deticilos ni eza 56 d� 46 smialc taht stimbus y]luftcvps� si foereht eciton ylrae na dna ecnawolla y� erofereht t�cilppA rof noitidnoc o� OPE fo �o� t�ic�u� to� ro� �solcs� OPE � �c g�c�pfo �m g� rof clb� � �wc� eb �p c� �n� .sllec �ifi� otomiguS � �tage� on ti d� ec�f� e� � ��p a fo �usolcs� si �j�us c� � noi� m� � �F .elb� � � �di�c si �o1� e�fi � �om�uS �vo re� elb�t� e� � � � t� � t�A � y� � �d �z � OPE fo le�l wol ylev�al� a t� � y�o tub �cu�p OPE y� fo � c� ,�F .t� nrobuS �if�c � u�l� c� �� c�f� si sll� y� fo tis�d oN .ll�c di�l�hp�l c�el a � gn� �dd� � � sllec romut ycnd�l gn�mts ch� tceles ro niatbo Case 1:05-cv-12237-WGY Document 312-15 Filed 03/05/2007 Page 7 of 8 67499800 CTI-MA 908411076MA J 255 92724 A O�2S+ 81$x n�alo t�d�:qlt �n a fo �rara�:lA tsriF sm[alG latoT 0 �riU )s( "'if'( ')s( )4( )� )2( )�( �81 PUORG :de=euqmsinoisn�msi�tdihwrofreilmr�d'�d'noldennocnl�ropserA � � ,:,r oa". :)�(�t.1 �FC73redruemit�onols�xS�Ml)s�uqsr)s(�:([l� � :STNETAP �:I RENOI�SI�0O T/�/ATSlSSA EHTOT :� �coo � RETTEL LArTIMSNART T/1EMDNE�A NOITAZIROHTUA EEF Case 1:05-cv-12237-WGY Document 312-15 Filed 03/05/2007 Page 8 of 8

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